Psychology
Good mood helps boost brain power in older adults
Older adults can improve their decision making and working memory simply by putting on a happy face, a new study suggests. Researchers found that easy mood-boosters — like giving people a small bag of candy — helped seniors do significantly better on tests of decision-making and working memory.
This is the first study to show the power of positive moods in helping older people with these brain tasks. “There has been lots of research showing that younger adults are more creative and cognitively flexible when they are in a good mood. But because of the cognitive declines that come with aging, we weren’t sure that a good mood would be able to help older adults,” said Ellen Peters, co-author of the study and professor of Psychology. “So these results are good news. There are ways for older adults to overcome some of the cognitive declines that come with aging.”
The study involved 46 adults aged 63 to 85. Half of them were put into a good mood by receiving a thank-you card and two small bags of candy, tied with a red ribbon, when they arrived at the lab for the experiment. The other “neutral mood” participants did not receive a card or candy.
“Given the current concern about cognitive declines in the aged, our findings are important for showing how simple methods to improve mood can help improve cognitive functioning and decision performance in older adults, just like they do in younger people,” Peters said.
osu.edu/researchnews/archive/goodmoodsenior.htm
Pharmacy
Zinc helps against infection by tapping brakes in immune response
New research suggests that zinc helps control infections by gently tapping the brakes on the immune response in a way that prevents out-of-control inflammation that can be damaging and even deadly. Scientists determined in human cell culture and animal studies that a protein lures zinc into key cells that are first-responders against infection. The zinc then interacts with a process that is vital to the fight against infection and by doing so helps balance the immune response.
This study revealed for the first time that zinc homes in on this pathway and helps shut it down, effectively ensuring that the immune response does not spiral out of control. The team led by Ohio State University researchers also found that if there is not enough zinc available at the time of infection, the consequences include excessive inflammation. In this research, zinc’s activity was studied in the context of sepsis, a devastating systemic response to infection that is a common cause of death in intensive-care unit patients. But scientists say these findings might also help explain why taking zinc tablets at the start of a common cold appears to help stem the effects of the illness.
“We do believe that to some extent, these findings are going to be applicable to other important areas of disease beyond sepsis,” said Daren Knoell, senior author of the study and a professor of Pharmacy and Internal Medicine. “Without zinc on board to begin with, it could increase vulnerability to infection. But our work is focused on what happens once you get an infection — if you are deficient in zinc you are at a disadvantage because your defense system is amplified, and inappropriately so.”